Should cases without suspects be submitted?

Yes, if there is no suspect and there is evidence from the crime scene, a DNA profile can be obtained and entered into the Combined DNA Index System (CODIS) database to attempt to develop an investigative lead. If there is a CODIS hit to an unknown suspect, then a hit letter will be sent to the investigator. At that time a known buccal swab should be obtained from the individual and submitted to the laboratory. Comparisons will then be made between the known reference sample and the evidence submitted.